Season 3
Desus & Mero
58 EPISODES • 2021
Season 3 of Desus & Mero was released on January 31 and consists of 58 episodes.

Season 2

Episodes

1: RIGHT OFF THE RIP
Jan 31, 2021
Illustrious guest: Stacey Abrams
2: COOK-'EM-ALL
Feb 4, 2021
Illustrious guest: Freddy Gibbs
3: THAT'S ON Y'ALL
Feb 7, 2021
Illustrious guest: Jazmine Sullivan
4: I SMELL BROKE
Feb 11, 2021
Illustrious guest: Whoopi Goldberg
5: PASSIVE-AGGRESSIVE G.O.A.T.
Feb 14, 2021
Illustrious guests: Zendaya & John David Washington English
6: WE BE HERE, HE BE THERE
Feb 18, 2021
Illustrious guest: Anthony Mackie
7: MOVE TO UTICA
Feb 21, 2021
Illustrious guest: Ludacris
8: BIRD COUSINS
Feb 25, 2021
Illustrious guest: Kelly Rowland
9: THE WILD CRANIUM
Feb 28, 2021
Illustrious guest: Travis "Taco" Bennett
10: EAST COAST REGGIE
Mar 4, 2021
Illustrious guest: Ramy Youssef
11: MAD MOIST
Mar 7, 2021
Illustrious guest: Delroy Lindo
12: DON’T COME TO MY FUNERAL
Mar 11, 2021
Illustrious guest: Eddie Huang
13: PIPES O’CLOCK
Mar 14, 2021
Illustrious guest: Phoebe Bridgers
14: PUFF OF FEATHERS
Mar 18, 2021
Illustrious guest: Eddie Murphy
15: MY LITTLE MULE
Mar 21, 2021
Illustrious guest: 24kGoldn
16: L MACHINE
Mar 25, 2021
Illustrious guest: Kenan Thompson
17: FUTURE HATS
Apr 8, 2021
Illustrious guest: Glenn Close
18: HALF A LIP
Apr 11, 2021
Illustrious guest: Andra Day
19: WEEKEND DAD
Apr 15, 2021
Illustrious guest: Miguel
20: TWERKING FOR NO ONE
Apr 18, 2021
Illustrious guest: J Balvin
21: THE CHEEK DETECTIVE
Apr 22, 2021
Illustrious guest: Issa Rae
22: THE PLATYPUS OF SALADS
Apr 25, 2021
Illustrious guest: Demi Lovato
23: YO FREE KNOWLEDGE
Apr 29, 2021
Illustrious guest: Julian Edelman
24: ONE WOOD
May 2, 2021
Illustrious guest: Taylour Paige
25: WALL OF ZEPPOLES
May 6, 2021
Illustrious guest: Yo-Yo Ma
26: STURDY LIMBS
Jun 20, 2021
Illustrious guest: Lil Nas X
27: WATERMARKED X-RAYS
Jun 24, 2021
Illustrious guest: Yara Shahidi
28: MID-NUP
Jun 27, 2021
Illustrious guest: Don Cheadle
29: FULL BODY TOPPY
Jul 1, 2021
Illustrious guest: Migos
30: MAD HABITAT
Jul 8, 2021
Illustrious guest: Benny Blanco
31: YEARLY BERET BUDGET
Jul 11, 2021
Illustrious guest: Vince Staples
32: KETCHUP & OYSTERS
Jul 15, 2021
Illustrious guest: Barry Jenkins
33: SEA OF UNCLES
Jul 18, 2021
Illustrious guest: Cynthia Erivo
34: BANG YOUR LITTLE HAMMER
Jul 22, 2021
Illustrious guest: H.E.R.
35: STAYING IN THE DRAFTS
Jul 25, 2021
Illustrious guest: Bobby Shmurda
36: SPACE LAW
Jul 29, 2021
Illustrious guest: Matt Damon
37: YIELD TO REBINNERS
Aug 1, 2021
Illustrious guest: Zazie Beetz
38: AKA HARRY NUGS
Aug 5, 2021
Illustrious guest: Eric André
39: THROW THE MID
Aug 8, 2021
Illustrious guest: Idris Elba
40: SCAMMING FEE
Aug 12, 2021
Illustrious guest: Marlon Wayans
41: ORIGINAL HAIRLINE
Aug 15, 2021
Illustrious guest: Chance the Rapper
42: WILD VENOMOUS
Aug 19, 2021
Illustrious guest: John Turturro
43: IT MIGHT BE REGGAETON
Oct 17, 2021
Illustrious guest: Nas
44: NOT GUILTY, YOUR MAJESTY
Oct 21, 2021
Illustrious guest: Lewis Hamilton
45: WILD ROMANTICAL
Oct 24, 2021
Illustrious guest: Baby Keem
46: AFRICAN AMERICAN CHLOROPHYLL
Oct 28, 2021
Illustrious guest: Dave Grohl
47: PRAYER WARRIORS ASSEMBLE
Oct 31, 2021
Illustrious guest: Yvonne Orji
48: TODDLER LEVEL CONFIDENCE
Nov 4, 2021
Illustrious guest: A$AP Rocky
49: CLOWN-LIKE ACTIONS
Nov 7, 2021
Illustrious guest: Cordae
50: WEST INDIAN DAD FEET
Nov 11, 2021
Illustrious guest: Dwayne Johnson
51: OVARY MAJORA
Nov 14, 2021
Illustrious guest: Keke Palmer
52: JUST ASKING QUESTIONS
Nov 18, 2021
Illustrious guest: Jeff Goldblum
53: CO-POTATOING
Nov 21, 2021
Illustrious guest: Kevin Hart
54: A VERY ROASTABLE SHIRT
Dec 2, 2021
Illustrious guest: Tracy Morgan
55: STEAMED STEAK
Dec 5, 2021
Illustrious guest: French Montana
56: SUSHI HOT DOGS
Dec 9, 2021
Illustrious guest: Sandra Bullock
57: 110% POLYESTER
Dec 12, 2021
Illustrious guest: Michael B. Jordan
58: BONG, DONE, FINITO
Dec 16, 2021
Illustrious guests: Keanu Reeves and Carrie-Anne Moss
Season 4
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